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Confirmatory diagnostic studies should be performed prior to initiating therapy, if possible, and the patient should be followed with appropriate studies to demonstrate hematologic improvement (Hgb, hematocrit, RBC, reticulocyte count)
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This early response may reflect the body's immediate utilisation of available B12 for urgent metabolic processes
Over a couple of months of steady treatment, people who had tingling or numbness from very low levels may notice gradual improvement
Individual response varies based on age, injury severity, dosing protocol, and overall health
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