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maintained endothelial function by correction of obesity-induced decreases in endothelial nitric oxide synthase (eNOS), reduced markers of hypertrophy and fibrosis

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doi: 10.1097/mca.0000000000000830 13 SilverHJOlsonDMayfieldDWrightPNianHMashayekhiMet al

Furthermore, animal and clinical studies have shown that glutamine deficiency leads to villous atrophy (destruction of villi) and mucosal ulcerations (sore lesions) in the small intestine, leading to an impairment in the functioning of immune cells, and resulting in greater susceptibility to infections