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Some patients choose to continue semaglutide indefinitely as a chronic disease management tool, while others use it as a reset period to build new patterns and then transition to lower doses or discontinuation

Thomas MK, Nikooienejad A, Bray R, Cui X, Wilson J, Duffin K, Milicevic Z, Haupt A, Robins DA

Case studies highlighting successful management of these side effects through dose adjustment and patient education are common, illustrating the importance of healthcare provider support in the early stages of treatment

This creates a frustrating illusion of a stall when fat loss is actually continuing normally underneath the constipation weight

The STEP 1 trial extension showed that participants regained two-thirds of their prior weight loss within one year of stopping