The only FDA approved therapy for RP is Luxturna (Spark Therapeutics), a subretinal gene therapy to correct RPE65 -induced retinal degeneration
doi:10.1001/jama.2024.9217
21 GallagherE
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Moreover, they generate most of the chemical energy (e.g., through the citric acid cycle and the electron transport chain) needed to power the cells biochemical reactions and, thereby, they are a source for free radicals