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In addition to effects directly on the activity of BCKD, the inhibition of MPC leads to activation of AMPK with the result being alterations in various metabolic processes that, in turn, reduce the level of phosphorylation of BCKD with the consequences being increased metabolism of BCAA

(7) Corazza O, Martinotti G, Santacroce R, Chillemi E, Di Giannantonio M, Schifano F, Cellek S

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The increased positivity rates for methamphetamine in urine test results were bolstered by similar patterns in other specimen types