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In vivo, BPC-157 demonstrates robust efficacy in rodent models, accelerating healing of skin wounds, muscle tears, tendon and ligament injuries, and gastrointestinal ulcers

More long-term studies in humans are needed

Lilly submitted the diabetes NDA in October 2021, the FDA approved Mounjaro in May 2022, and the obesity approval (Zepbound) followed in November 2023

Though peptides in general are gaining traction across a range of therapeutic frontiers, from rare diseases to neurodegenerative conditions such as Alzheimers, the rise of GLP-1s as a blockbuster therapy for chronic weight management has redefined the field of peptide manufacturing