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J Cereb Blood Flow Metab 30(6):11211136 Wen J, Qian S, Yang Q, Deng L, Mo Y, Yu Y (2014) Overexpression of netrin-1 increases the expression of tight junction-associated proteins, claudin-5, occludin, and ZO-1, following traumatic brain injury in rats

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This is consistent with GHK-Cus known role in upregulating collagen synthesis in dermal fibroblasts, a mechanism confirmed in a comprehensive review in Biomolecules documenting GHK-Cus influence across more than 4,000 human genes involved in tissue remodeling and repair

Role of gut microbiota in the development of insulin resistance and the mechanism underlying polycystic ovary syndrome: a review

This effect should be considered when timing supplements and other medications