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GHRH/GHRP synergy characterisation: Foundational studies by Bowers, Thorner, and colleagues established that GHRH and synthetic GHRPs act through complementary pituitary signalling pathways cAMP and calcium respectively to produce synergistic GH release substantially exceeding that of either stimulus alone

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Physical therapy integration Synergistic benefits: Physical therapy provides mechanical stress stimulating tissue remodeling (Wolff's Law for bone, mechanical loading for tendon/ligament)