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One promising avenue involves the use of new inhibitors that target major ROS-producing systems, such as HO-1 expression

The science backs this up too: lab and animal studies confirm it lowers melanin by blocking tyosinase and the more you use (up to a point), the more it works

Wu J, Chernatynskaya A, Pfaff A, Kou H, Cen N, Ercal N, et al

Additionally, by targeting non-cancerous senescent cells, senolytics may help reduce tumor formation risk, limit recurrence, and slow disease progression

Also known as 5 amino 1 methylquinolinium, its structure has made it a subject of interest for investigating NNMT activity and related cellular metabolic pathways