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Indications: Huntington's Chorea (a hyperkinetic movement disorder) A drug of first choice for this condition Side Effects: Sedation Depression (suicidal tendencies) Parkinsonism symptoms Lacks the hypotensive & GI side effects of reserpine due to its selectivity for central VMAT2 Pharmacokinetics: * undergoes rapid hepatic metabolism involving carbonyl reductase and CYP2D6 to 2 active metabolites -dihydrotetrabenazine (-HTBZ) and -dihydrotetrabenazine (-HTBZ), with eventual renal elimination of metabolites the -HTBZ and -HTBZ metabolites are primarily responsible for the pharmacological & therapeutic effects produced by the parent prodrug Readily crosses the blood brain barrier & depletes cerebral monoamine stores
Suzan Pucci 42.252 CRF-SP Certido de Regularidade nr: 58.473(CRF PJ) AE: 140.007.3 | AFE: 083.457.8 | Licena Sanitria-CMVS: 3550308 Oferta de Frete Grtis para sua Regio FRETE GRTIS POR REGIO a partir de So Paulo e Sudeste: R$ 150,00 p/ pedido Sul: R$ 199,00 p/ pedido Centro-Oeste: R$ 209,90 p/ pedido Nordeste: R$ 320,00 p/ pedido Norte: R$ 580,00 p/ pedido
For more comprehensive benefits, we also recommend our Wellness Infusion or Skin Health IV therapies
Support it by: limiting alcohol reducing junk food staying hydrated avoiding supplement overload Glutathione supports liver pathways, but lifestyle still leads
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