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In addition to decreased downstream hormone levels, low DHEA may be associated with aging, fatigue, increased cardiovascular disease, bone loss, low libido, erectile dysfunction in men, and cognitive performance

PMID 27806244

I tell patients up front

The sample was further purified via size exclusion using a HiLoad 26/60 Superdex 75 pg gel filtration column and equilibration buffer (20 mM Tris pH 8.0, 150 mM NaCl, 5 mM -mercaptoethanol)

Nayan Patel, he suggests that consistent low daily doses are likely more useful than a single high-dose IV drip once a month, unless something specific is going on that warrants it