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The fact that this patient tolerated oral semaglutide suggests that formulation, route of administration, or specific receptor binding profile may matter
Chronic administration of high doses of oral levocarnitine in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine and trimethylamine-N-oxide, since these metabolites are normally excreted in the urine
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What they did: Review article in Science
