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Unlike most peptides that originate from nuclear DNA, MOTS-c is encoded within the mitochondria, offering unique metabolic effects at the cellular energy level
Direct oxidation of GSH to GSH through free radical intermediates formed from 15-HpETE-PE before it is metabolized could also occur
As an example, GSTZ1-1 catalyzes the cis-trans isomerization of 4-maleylacetoacetate to 4-fumarylacetoacetate within the phenylalanine catabolic pathway 21
Concrtement, le glutathion est encapsul dans de minuscules vsicules lipidiques qui le protgent dans le tube digestif et facilitent son passage dans la circulation sanguine
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