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Association with exaggerated distal intestinal hormone release

GCL is in part regulated by GSH feedback inhibition, thus if GSH is depleted due to oxidative stress, inflammation, or exposure to xenobiotics, de novo synthesis of GSH is upregulated, as is cysteine synthesis

Multiple reviewers were surprised by this, expecting a flat rate throughout treatment

Typical conversions from animal studies use body-surface-area scaling: Rat dose: 10 g/kg human equivalent ( 0.162) 1.6 g/kg For a 70 kg adult: ~112 g per day Self-experiment protocols often cite 100200 g once or twice daily via subcutaneous injection

Studies show that GLP-1 drugs need to work on the brain to help with weight loss which means they may change more than just your appetite