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It wasnt until the late 2010s that doctors and patients started considering and using GLP-1 drugs specifically for weight management, with celebrities and the rich spearheading the trend

doi: 10.1152/ajpendo.00211.2007

In 2005, an Eli Lilly-funded study admitted that 44% of Cymbalta users experienced withdrawal symptoms, though the company described them as mild or moderate. An independent research published in Addictive Behaviors supported Eli Lillys research, finding that half of patients attempting to quit Cymbalta experienced withdrawal symptoms

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Todo ello hace que existan diferencias entre ellos en cuanto a su potencia en reduccin de HbA1c, glucemia basal o la reduccin ponderal, entre otros factores, que deben considerarse al elegir frmacos de esta familia78,83,84