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As expected, 13-month-old KO animals were still glucose intolerant (Fig
We further determined the impact of ERMCS-localised GLP-1R signalling on -cell function by analysing acute insulin secretion responses and -cell survival to ER stress induction downstream of GLP-1R stimulation in SPHKAP RNAi-treated versus Control WT INS-1 832/3 cells
Abdominal visceral fat and the ratio of trunk to lower extremity fat were reported by the researchers to be significantly reduced
Published 2018 Aug 8
Sustainable results require combining GLP-1 therapy with a balanced diet, regular physical activity and ongoing medical guidance
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