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Severe neurological damage from prolonged deficiency can become permanent if not treated promptly which is why accurate and timely diagnosis matters more than choosing a particular supplement form
This finding aligns with current AAFP clinical guidance recommending oral therapy as a first-line option for most patients
Structurally, the quaternary nitrogen at position 1 carries a permanent positive charge that no change of pH removes
GPs will normally give their patients B12 injections every 12 weeks, but normally the effects will wear off before this time
Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substance that carries oxygen in red blood cells
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