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1A) had been reported to potentiate GLP-1R-mediated cAMP signaling in response to weak peptidic agonists, including the GLP-1 metabolite GLP-1(936)amide ( 21 ) and the GLP-1R/glucagon-receptor dual agonist oxyntomodulin ( 22 )

After CTF refinement, Bayesian polishing in Relion, and further refinement in cryoSPARC 49 , a wtVLP map was obtained at a resolution of 2.95

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Niini T, Laakso A, Tanskanen P, Niemel M, Luostarinen T

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