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Very high-intensity training or significant caloric deficit from excessive exercise can suppress the hypothalamic-pituitary-ovarian (HPO) axis, leading to disrupted ovulation, a condition known as hypothalamic amenorrhoea. Your goal is consistent, moderate activity rather than intense training regimens

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1 Your ability and willingness to adopt lasting diet and exercise changes to maintain weight loss after stopping the medication are major factors

Individuals with more significant baseline weights or metabolic conditions may experience more substantial transformations