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Patients with HbA 1c 8.0% at screening reduced their insulin dose by 20% at start of the trial to reduce the risk of hypoglycemia
Some of these medications (liraglutide, semaglutide, and dulaglutide) have demonstrated cardiovascular benefits in clinical trials, with Wegovy specifically approved for reducing cardiovascular risk in adults with established cardiovascular disease and either obesity or overweight
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