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3.4.3 Brainstem GLP-1R expression and functional boundaries At the brainstem level, GLP-1 receptors (GLP-1Rs) are expressed in multiple neuronal populations within the NTS, including PPG neurons and GABAergic neurons (22)
It contains the active ingredient semaglutide, a GLP-1 weight loss drug that works by regulating appetite and controlling food intake
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Semaglutide is 94% structurally homologous to human GLP-1, but has important modifications to achieve a longer half-life of approximately 1 week [6, 7]
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