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Table 9: Results at Week 52 in a Trial Comparing TRESIBA to Insulin Glargine U-100 in Adult Patients with Type 2 Diabetes Mellitus on OAD(s)* *OAD: oral antidiabetic agent **The change from baseline to end of treatment visit in HbA1c was analyzed using ANOVA with treatment, region, sex, and anti-diabetic treatment at screening as fixed effects, and age and baseline HbA1c as covariates

Hepatology 28: 45-49

the remainder passes through the digestive tract intact

However, there is one major difference that separates retatrutide from tirzepatide: retatrutide targets three hormone receptors, while tirzepatide targets two

Studies have explored these peptides in endocrine and metabolism focused experimental models