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For imaging, superparamagnetic iron oxide NPs (SPIONs) decorated with exendin-4 were encapsulated in phospholipid bilayers, forming magnetoliposomes with a T 2 relativity of 220 mM 1 s 1 that permit -cell magnetic resonance imaging (MRI) without additional contrast agents [120]
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However, in the case of iron overload, the uptake of non-transferrin-bound iron (NTBI) increases, mediated by metal transport proteins such as SLC39A14
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