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Since DSIP is not FDA-approved, its long-term safety, purity, and dosing are uncertain

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If any side effects emerge, they may adjust your dosage or take other measures to alleviate your symptoms

"We also want to determine whether other GLP-1 drugs can deliver the same relief, possibly with even fewer gastrointestinal side effects," Braca said in the same press release.

Multiple other causes should be considered including peripheral vascular disease, neuropathy, medication effects from other drugs (particularly diuretics, beta-agonists, and statins), hypothyroidism, pregnancy, and musculoskeletal conditions