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Key mechanistic observations from laboratory studies: G-actin sequestration: TB-500 binds monomeric G-actin, regulating the pool available for filament polymerization
Practically this means that the infant need to be fed often during the first days to stimulate the milk coming in
If the blood is visibly haemolysed (lots of burst blood cells) the lab will not do the B12 test for that reason
These outcomes align with the local effect theory
But in general, these folks are more likely to be B12 deficient: vegetarians or vegans people taking certain medications (like metformin, Prilosec, or Pepcid) pregnant and breastfeeding people people over 50 people with atrophic gastritis, celiac disease, Crohns disease, or who have had stomach or intestinal surgery Which form of vitamin B12 is best
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