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GLP-1 receptor activation has independent anti-inflammatory effects in animal and human studies
Combined, these effects can produce clinically significant cardiovascular stress, particularly in patients with pre-existing heart conditions or uncontrolled hypertension
The idea of microdosing these drugs first gained traction due to obesity drug shortages shortly after their approval by the U.S
The back of the upper arm, in the fatty area between the shoulder and elbow, works well but is harder to self-administer
The NAION connection The link between GLP-1 medications and NAION is newer and still being actively researched
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