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Types of GLP-1 medications GLP-1 therapies are available in several different forms: Once-weekly injections Daily oral or injectable options Combination therapy with insulins Xultophy (insulin degludec + liraglutide) IcoSema (weekly insulin Icodec + Semaglutide) Soliqua (insulin glargine and lixisenatide) How the main GLP-1 drugs compare While all GLP-1 medications work through similar mechanisms, they differ in strength, dosing frequency, weight loss effects, and side-effect profiles
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1 Introduction The gutbrain peptide, glucagon-like peptide-1 (GLP-1), is encoded by the proglucagon (PPG) gene, which is expressed in the intestines and pancreas [for a review, see PPG gene is also expressed in the olfactory bulb ( The extensive physiological and behavioral effects of GLP-1 are mediated by the GLP-1 receptors (GLP-1R), which are expressed in both the central and autonomic nervous systems ( Following ingestion of a meal, the GLP-1 levels rapidly increase
