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It is majorly found circulating in the blood as GLP-1(7-36) amide that is produced primarily from three tissues of the human body: enteroendocrine L cells in the distal small bowel, cells in the pancreas, and the central nervous system (1, 2)
Treatment decisions are individualized and discussed during your visit
However, a more effective approach for weight loss and maintenance would involve strategies that both suppress appetite and promote energy expenditure
This may result in an unpleasant, stinging sensation at the site of administration
(2023) Retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in type 2 diabetes N Engl J Med 389(6):503-513
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