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We conclude with a critical assessment of challenges that need to be overcome before successfully employing synaptic density biomarkers as diagnostic and/or prognostic tools in the study of neurological and neuropsychiatric disorders
More than a sidekick: glia and homeostatic synaptic plasticity
Research suggests benefits for inflammatory bowel conditions, gastric ulcers, esophageal damage, and gut lining integrity
Mechanistically, it acts systemically: it sequesters G-actin, promotes endothelial cell migration in scratch-wound assays, and has shown progenitor-cell mobilization signals in preclinical cardiac models
The results have been consistently promising across multiple tissue types and organ systems, though large-scale human clinical trials remain limited
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