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Patients presented the largest weight loss reported to date with that drug class, prompting Novo Nordisk to conduct additional studies on semaglutide and other GLP-1Ra in people living with obesity (PwO) [18, 19]
Alteraciones metablicas y endcrinas (diabetes mellitus, resistencia a insulina, cetoacidosis diabtica, hiperlipoproteinemia, obesidad endgena, hipotiroidismo, hipopituitarismo, enfermedad de Addison y sndrome de Cushing)
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5 The GLP-1 and GIP components reduce appetite and improve insulin sensitivity
Eligible participants had CKD defined as either an eGFR of 5075 mL/min/1.73 m 2 with UACR 3005,000 mg/g, or an eGFR of 25 to 50% eGFR decline, ESKD, or all-cause mortality [81]
