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Statements Acknowledgments The authors acknowledge financial support from Department of Science and Technology to PP and Department of Biotechnology to AVM

In 2010, quercetin supplements were added to the Food and Drug Administrations Generally Recognized as Safe (GRAS) list as a supplementary ingredient in foods and beverages up to 500 mg per serving (Dabeek and Marra, 2019)

Selenium-dependent enzymes, such as glutathione peroxidases (GPXs) and thioredoxin reductases, are crucial in lowering oxidative stress because they neutralize ROS and protect cell membranes from lipid peroxidation