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It is found in high concentrations in muscle and brain tissue, where it provides antioxidant support and helps protect proteins and cells from oxidative stress
J Huazhong Univ Sci Technolog Med Sci 25:501504
Additionally, DPP-4 inhibitors have been shown to improve abnormal liver transaminases levels such as aspartate aminotransferase and alanine transaminase, in patients with T2DM with liver dysfunction
[19] [20] En el cerebro, la activacin del receptor de GLP-1 se ha relacionado con efectos neurotrficos que incluyen neurognesis, [21] [22] y efectos neuroprotectores que incluyen sealizacin necrtica reducida [23] y apopttica [24] [23] muerte celular, [25] [26] y disfunciones
Incretin-based therapy and pancreatitis: accumulating evidence and unresolved questions
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