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Consistent with in vitro findings that demonstrated the preferential cellular uptake of OA-NPs@OA and potent suppression of aberrant keratinocyte proliferation, the optimized cutaneous pharmacokinetic profile enabled enhanced OA delivery to target cells while minimizing systemic exposure

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Methylation can be impaired because SAM production is inadequate, because SAH accumulates and inhibits methyltransferase enzymes, or because both problems occur together

Delta sleep-inducing peptide and Deltaran: Potential approaches to antistress protection. Neuroscience and Behavioral Physiology 38 1 (2008): 953957

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