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The latest research showed that low-dose metformin targets the lysosomal AMPK pathway to decrease hepatic triglyceride levels through the PEN2-ATP6AP1 axis in an AMP-independent manner
1b), mitochondrial DNA (mtDNA relative to total genomic DNA per cell
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12 Dynamic changes and interactions of immune cells in the joint region of OA 12.1 Dynamic changes among immune cells in the OA joint During the progression of osteoarthritis (OA), the dynamic changes in immune cells are a critical feature of disease development, spanning from the early inflammatory phase to the late cartilage destruction phase
