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While these drugs are designed for long-term use in disease management, many individuals use GLP-1s for a limited periodeither to jump-start weight loss before transitioning to a lifestyle-based maintenance or due to financial constraints

If systolic blood pressure falls below 90 mmHg or the patient becomes symptomatic, a prompt review of the antihypertensive regimen is warranted

Large RCTs of long-enough duration and follow-up are warranted for the safe treatment of pigmentary disorders

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