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Key Takeaways Melanotan I and II darken skin without long sun exposure, but they come with potential side effects you must weigh

The study titled Off-label antiobesity treatment in patients without diabetes with GLP-1 agonists in clinical practice and published in Hormone and Metabolic Research indicates that 58% of patients reported side effects mostly concerning the gastrointestinal tract. In addition, more than 20% of the participants quit the drug because of intolerable side effects. This study certainly put Novo Nordisk on risk of bowel injuries associated with the use of Ozempic

Early evidence suggests substantial weight loss potential in clinical trials

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GLP-1 agonist initiation could be done in primary care, as long as primary care doctor and team are comfortable