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In that case, the T-cells responsible for those regulations begin to divide rapidly and become pro-inflammatory, leading to a drought of Th1 and Th17 T-cells [4]
Recent research highlighted the critical role of the gut microbiota in maintaining the integrity of the intestinal barrier, primarily through its influence on tight junctions (TJs) (36)
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For example, growth hormone is implicated in activating bone turnover, increasing body lean mass, and reducing adiposity
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