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While more robust human studies are needed, current research suggests it may become an important component of future healthy aging and longevity strategies

However, despite a growing interest in mapping the post-translational 20 , metabolic 21 and lipidomic 22,23 landscapes of AML, a unified multiomic classification that can be clinically exploited is currently lacking

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Chromatins were sonicated to 2001000 bp and immunoprecipitated with antibodies against NRF2, H3K4Me3, and H3K9Ac and determined with gene-specific primers (Supplementary Table 1)