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The aim is to separate promising ideas from treatments that have been properly tested in humans, especially when Crohns disease or ulcerative colitis may be active

Our study may prove that these endpoints are not suitable for irritancy testing of copper compounds in a monolayer HaCaT assay

Chang W, Zhang M, Li J, Meng Z, Wei S, Du H, Chen L, Hatch GM (2013) Berberine improves insulin resistance in cardiomyocytes via activation of 5-adenosine monophosphate-activated protein kinase

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However, the authors suggest that future larger and longer trials are needed to fully assess the efficacy and safety of this treatment combination