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The LEADER trial was an international, randomised, double-blind, controlled cardiovascular outcomes trial (CVOT)
fewer physical symptoms Weeks 6-8: Significant improvement in both physical and mental anxiety symptoms Weeks 8-12: Full therapeutic benefits typically emerge Patience during those initial weeks pays off with more stable, long-lasting relief
Subsequent studies expanded into musculoskeletal healing, vascular biology, and regenerative medicine
E., & Shin, S
Wisniewski, J
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