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The rationale for combining them is mechanistic complementarity
So, this enhances ATP synthesis and body rate
Dermatological Side Effects Cardiovascular concerns aside, tirzepatide can also cause dermatological side effects, including skin itching, rash, or redness, as well as swelling of the eyelids or around the eyes, face, lips, or tongue
If your bottle doesnt have one, be sure to keep an eye out for significant darkening or discolouration (the product will usually become coppery or brownish) which can be a sign of oxidisation
Unlike the GLP-1 agonists we're familiar with, retatrutide is a triple agonist targeting GIP, GLP-1, AND glucagon receptors
