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Moreover, TGR5 activation protects against inflammation induced by lipopolysaccharide (LPS) by suppressing the production of proinflammatory cytokines mediated by NF-B pathway (Wang et al., 2011)
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Such a milestone once felt impossible for the 35-year-old who recalls growing up at the height of "heroin chic," a time in the early aughts when celebrities like Paris Hilton and Nicole Richie appeared in tabloids looking extremely thin
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Furthermore, their multifaceted mechanisms of action suggest potential applications beyond traditional metabolic disorders
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