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The SURMOUNT-OSA trials revealed that Tirzepatide dramatically reduced obstructive sleep apnea severity by finding that the drug decreased case patients' apnea-hypopnea index (AHI), a measure of breathing interruptions, by an estimated 2024 events per hour more than controls, depending on whether patients were using positive airway pressure (PAP) therapy at baseline

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The beta-cell mass plays a critical role in obesity duration, in which pancreatic fat contents increase and are suggested to cause beta-cell dysfunction, resulting in a worsening glycemic control [2]

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