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These medications slow gastric emptying and increase feelings of fullness while decreasing hunger and cravings

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However, these conventional host bacteria possess several inherent limitations, including vulnerability to extreme environmental conditions, potential self-toxicity, and inadequate colonization, which can hinder their therapeutic efficacy [5]

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Patients must also demonstrate commitment to lifestyle modification , as Wegovy is licensed only as an adjunct to a reduced-calorie diet and increased physical activity, not as monotherapy

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High body mass index (BMI) can also disrupt kidney function through non-diabetes-related pathophysiological mechanisms such as hemodynamic perturbations

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