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These findings suggest that the cardiovascular and kidney benefits of treatment with SGLT2is are worth the cost for all people with type 2 diabetes, regardless of use of other medications or their HbA 1c levels
As more patients arrive having researched therapies with AI, physicians will need to spend as much time discussing the quality of the evidence as the proposed mechanism.
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Reduced efficacy concerns GLP-1 receptor agonists are designed to work at specific doses to achieve optimal receptor activation (saturation) and to provide full therapeutic effect
