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Interestingly, IF may transiently elevate testosterone levels, likely due to a short-term compensatory increase in LH secretion triggered by energy restriction [56]

Oxidative stress markers: Elevated levels of methylglyoxal (MG) and decreased superoxide dismutase (SOD) activity are associated with DPN, reflecting increased oxidative stress

Unlike classic dietary antioxidants (vitamin C, vitamin E) which localize to specific compartments, melatonin being both lipophilic and hydrophilic distributes through all cellular compartments, especially concentrating in mitochondria where the majority of ROS are produced

Las grasas son metabolizadas en el interior de la mitocondria celular en un proceso llamado beta oxidacin