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1995 (Clinical Chemistry)
For diabetic retinopathy, there is some evidence to suggest that rapid improvements in blood sugar levels can lead to a temporary worsening of this condition
Tirzepatide Evidence: SURMOUNT-1 Three-Year Results The most dramatic diabetes prevention data comes from the SURMOUNT-1 trial three-year extension in participants with prediabetes, published in the New England Journal of Medicine in November 2024
(2025) further demonstrated in animal studies that IPA supplementation inhibited the NLR family pyrin domain containing 3(NLRP3) inflammasome via AhR activation, ameliorating dehydroepiandrosterone (DHEA)-induced PCOS phenotypes in mice, including restored ovarian morphology, improved insulin sensitivity, and normalized hormone levels (26)
00:00:11 Narrator On this episode, Associate Editor and Clinical Pharmacist Vickie Danaher reviews how the new oral version of semaglutide is changing how clinicians think about GLP1 medications for weight loss
