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Nausea (most common, typically dose-dependent and transient) Diarrhea or constipation during dose escalation Vomiting, especially when starting or increasing dose Reduced appetite and early satiety Injection site reactions (redness, bruising) Fatigue, particularly in early weeks Rare: Pancreatitis discontinue immediately with severe abdominal pain Rare: Thyroid C-cell effects (contraindicated with MEN2 or thyroid cancer history) Small-molecule NNMT inhibitor often discussed with metabolic protocols
AOD-9604 does not cause water loss or glycogen depletion the way GLP-1 agonists do, so there is no early "whoosh" effect
People with Chronic Fatigue or Low Energy Vitamin B12 injections can provide a significant energy boost for these individuals
Actually, in the 1950s, many people with a diagnosis of pernicious anaemia were treated with high doses of folate, as B12 injections were not yet available
Many of these symptoms are not specific to B12 deficiency but can also occur in other disorders
