LPO is implicated in human cataractogenesis because the toxic peroxidation products induce fragmentation of soluble lens proteins and damage vital membrane structures, correlating with an increase in lens opacity and changes in the refractive properties of the lens 23
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In addition, with the recognition of various modes of cell death, the original necrosis or oncotic necrosis [79] was challenged to be apoptosis [14, 15], necroptosis [16, 17], and lately ferroptosis [18, 19] and even pyroptosis [20, 21]