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GLP-1 medications have generally been well-tolerated for long-term use, though they may have mild to moderate side effects such as nausea, vomiting, diarrhea, abdominal discomfort, or occasional constipation

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mechanism glp 1 receptor agonist Frontiers Advances in GLP-1 receptor agonists:

Importantly, although their glucose-lowering efficacy diminishes in advanced CKD, cardiovascular and kidney benefits remain preserved [111]

mechanism glp 1 receptor agonist Frontiers Advances in GLP-1 receptor agonists:

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